SNPnexus Web Annotation Tool

barts-and-london_sml

Barts Cancer Institute

Variants present in≥ sample(s)

Show variants unique to each sample

Known/Novel mutations:

Gene(s)

Genomic Consequence (Ensembl):

Global Allele Frequency (ALFA) ≤

Show also variants without population data

Welcome to the SNPnexus interactive Demo. This report was generated using a synthetic input dataset comprising variant profiles from six breast cancer patients, comprising three hormone receptor-positive cases (P1-P3) and three triple negative cases (P4-P6). The dataset was curated to include both shared and subtype-specific variants, allowing evaluation of comparative analytical workflows. The original sample files are available for download here.

Query ID: nar2026
Human Assembly: GRCh38 / hg38
Number of files: 6
Total number of variants: 303

pace These results will be available at this URL until Monday, March 30, 2026 at 9:53 p.m.. They will be deleted after that.

Filters:

Showing variants present in at least 1 sample(s)
Showing: All mutations
Genomic consequence: All

keyboard_double_arrow_down Jump to results

Cohort-wide Plots

Mutations presented at least in

Genes

Top Mutated Genes for Sample

Variant Summary for Sample

Predictor:

All significant pathways (p<0.05) in this query are presented in the Voronoi interactive plot, with colour intensity representing the significance of the pathways.
Click here to open the visualisation in a new window.

Results

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

COSMIC is only available for academic usage. Please contact the authors if you are interested in using this dataset for other purposes.

Top Mutated Genes for Sample

Variant Summary for Sample

Predictor:

All significant pathways (p<0.05) in this query are presented in the Voronoi interactive plot, with colour intensity representing the significance of the pathways.
Click here to open the visualisation in a new window.

Results

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

COSMIC is only available for academic usage. Please contact the authors if you are interested in using this dataset for other purposes.

Top Mutated Genes for Sample

Variant Summary for Sample

Predictor:

All significant pathways (p<0.05) in this query are presented in the Voronoi interactive plot, with colour intensity representing the significance of the pathways.
Click here to open the visualisation in a new window.

Results

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

COSMIC is only available for academic usage. Please contact the authors if you are interested in using this dataset for other purposes.

Top Mutated Genes for Sample

Variant Summary for Sample

Predictor:

All significant pathways (p<0.05) in this query are presented in the Voronoi interactive plot, with colour intensity representing the significance of the pathways.
Click here to open the visualisation in a new window.

Results

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

COSMIC is only available for academic usage. Please contact the authors if you are interested in using this dataset for other purposes.

Top Mutated Genes for Sample

Variant Summary for Sample

Predictor:

All significant pathways (p<0.05) in this query are presented in the Voronoi interactive plot, with colour intensity representing the significance of the pathways.
Click here to open the visualisation in a new window.

Results

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

COSMIC is only available for academic usage. Please contact the authors if you are interested in using this dataset for other purposes.

Top Mutated Genes for Sample

Variant Summary for Sample

Predictor:

All significant pathways (p<0.05) in this query are presented in the Voronoi interactive plot, with colour intensity representing the significance of the pathways.
Click here to open the visualisation in a new window.

Results

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

Some of these scores are only freely available for academic usage. See the about page for more details and contact authors if you are interested in usage for commercial purposes.

COSMIC is only available for academic usage. Please contact the authors if you are interested in using this dataset for other purposes.